The induction of new bone and cementum formation. IV. Microscopic examination of the periodontium following human bone and marrow allograft, autograft and nongraft periodontal regenerative procedures.
The induction of new bone and cementum formation. IV. Microscopic examination of the periodontium following human bone and marrow allograft, autograft and nongraft periodontal regenerative procedures.
复制标题
诱导新骨和牙骨质形成。
DOI：
--
复制
发表时间：
1978
期刊：
影响因子：
--
通讯作者：
Albert James Aaronian
中科院分区：
文献类型：
--
作者：
W. H. Hiatt;R. Schallhorn;Albert James Aaronian
通过对100例自体骨和骨髓移植、同种异体骨移植和非移植再生术的人牙块切片和拔牙的组织学评价，结果显示：1.在所评价的79个部位中，有66个部位形成了新的牙骨质，而在21个部位中，只有7个部位发生了新的牙骨质形成。其中两个没有形成新牙骨质的移植部位只持续了14天。2.阻断切片评估显示39个移植部位中有33个有新骨形成，21个非移植部位中有7个有新骨形成。3.当再生确实发生时，如块切片所示，新附着的性质在所有移植入路中都是相似的，与健康功能的牙周组织相当。4.在自体移植和同种异体移植的方法中，已经证实了功能附着装置的再生潜力，包括新的牙骨质、骨和功能定向的牙周膜。5.临床、组织学和化学水平均未检测到对同种异体骨和骨髓移植的不良免疫反应。6.新鲜口腔内供体材料和冷冻自体或同种异体髂骨移植无强直或牙根吸收现象。在275个使用新鲜自体髂骨移植材料治疗的275个部位中，有16个在用非移植方法治疗的病例中观察到牙根吸收。
This retrospective study based on histologic evaluations of 100 human block sections and extracted teeth taken from sites treated via bone and marrow autograft, allograft and nongraft regenerative procedures revealed the following findings: 1. Graft procedures yielded new cementum formation in 66 of 79 sites evaluated while nongraft approaches yielded new cementum formation in only 7 of 21 sites. Two of the grafted sites not yielding new cementum were only 14 days duration. 2. Block section evaluation revealed new bone formation in 33 of 39 graft sites and in 7 of 21 nongraft sites. 3. When regeneration did occur, as seen in the block sections, the nature of the new attachment was similar in all graft approaches and was comparable to healthy functioning periodontium. 4. The potential for regeneration of a functional attachment apparatus including new cementum, bone and functionally oriented periodontal ligament has been demonstrated in autograft and allograft approaches. 5. Adverse immune response to bone and marrow allografts could not be detected at a clinical, histologic or chemical level. 6. No ankylosis or root resorption was noted with fresh intra-oral donor material and with frozen iliac autografts or allografts. Root resorption was noted in two cases treated with nongraft methods and in 16 of 275 sites treated with fresh iliac autograft material.