Localization of proteins to the Golgi apparatus
Localization of proteins to the Golgi apparatus
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DOI：
10.1016/s0962-8924(97)01197-5
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发表时间：
1998-01-01
影响因子：
19
通讯作者：
Munro, S
中科院分区：
文献类型：
--
作者：
Munro, S
为了使高尔基体发挥其各种独特的作用，它必须维持一定数量的常驻蛋白质。这些居民包括修饰通过高尔基体的蛋白质和脂质的酶，以及参与囊泡形成和蛋白质分选的蛋白质。对于这些居民中的几个，已经有可能确定，区域是至关重要的指定高尔基定位。考虑这些靶向结构域如何发挥作用，为高尔基体的组织及其蛋白质和脂质含量提供了见解。
For the Golgi apparatus to perform its various unique roles it must maintain a population of resident proteins. These residents include the enzymes that modify the proteins and lipids passing through the Golgi, as well as the proteins involved in vesicle formation and protein sorting. For several of these residents, it has been possible to identify, regions that are crucial for specifying a Golgi localization. Consideration of how these targeting domains could function has provided insights into the organization of the Golgi and its protein and lipid content.