Pharmacological and chemical effects of cigarette additives
Pharmacological and chemical effects of cigarette additives
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DOI：
10.2105/ajph.2005.078014
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发表时间：
2007-11-01
影响因子：
12.7
通讯作者：
Park, Candice
中科院分区：
文献类型：
--
作者：
Rabinoff, Michael;Caskey, Nicholas;Park, Candice
我们调查了烟草行业的文件和其他来源的证据，烟草添加剂可能的药理和化学作用。我们的研究结果表明，在599种记录在案的卷烟添加剂中，有100多种具有药理作用，可以掩盖卷烟发出的环境烟草烟雾的气味，增强或维持尼古丁的释放，增加卷烟的成瘾性，并掩盖与吸烟行为相关的症状和疾病。这些用途是否专门用于这些药物尚不清楚。我们的研究结果为烟草添加剂的监管控制提供了明确的依据。
We investigated tobacco industry documents and other sources for evidence of possible pharmacological and chemical effects of tobacco additives. Our findings indicated that more than 100 of 599 documented cigarette additives have pharmacological actions that camouflage the odor of environmental tobacco smoke emitted from cigarettes, enhance or maintain nicotine delivery, could increase the addictiveness of cigarettes, and mask symptoms and illnesses associated with smoking behaviors. Whether such uses were specifically intended for these agents is unknown. Our results provide a clear rationale for regulatory control of tobacco additives.