Adherence to Mediterranean diet and risk of prostate cancer
Adherence to Mediterranean diet and risk of prostate cancer
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DOI：
10.1080/13685538.2018.1450854
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发表时间：
2019-04-03
期刊：
影响因子：
2.6
通讯作者：
Rivas, Ana
中科院分区：
文献类型：
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作者：
Urquiza-Salvat, Noelia;Pascual-Geler, Manrique;Rivas, Ana
在欧洲，遵循传统地中海饮食 (MeDi) 的国家，特别是南欧国家，与其他欧洲地区相比，前列腺癌 (PCa) 的发病率和死亡率较低。在本研究中，我们调查了西班牙人群中 MeDi 与 PCa 相对风险和肿瘤侵袭性之间的关联。在个人评分组成部分中，发现患有前列腺癌的受试者比没有患前列腺癌的受试者更少食用橄榄油作为主要烹饪脂肪、蔬菜、水果和鱼类。然而，这些差异不具有统计学意义。大量摄入水果、蔬菜和煮熟的地中海番茄酱 (sofrito) 与前列腺癌侵袭性降低有关。结果显示，病例和对照之间地中海饮食模式的依从性得分没有差异，平均值分别为 8.37 +/- 1.80 和 8.25 +/- 2.48。然而，根据格里森评分，MeDi 与较低的 PCa 攻击性相关。因此，地中海饮食模式与 PCa 之间的关系仍无定论，值得进一步研究。需要进一步的大规模研究来阐明 MeDi 对前列腺健康的影响，以确定这种饮食在预防 PCa 中的作用。
In Europe, countries following the traditional Mediterranean Diet (MeDi), particularly Southern European countries, have lower prostate cancer (PCa) incidence and mortality compared to other European regions. In the present study, we investigated the association between the MeDi and the relative risk of PCa and tumor aggressiveness in a Spanish population. Among individual score components, it has been found that subjects with PCa were less likely to consume olive oil as the main culinary fat, vegetables, fruits and fish than those without. However, these differences were not statistically significative. A high intake of fruit, vegetables and cooked tomato sauce Mediterranean style (sofrito) was related to less PCa aggressiveness. Results showed that there are no differences in the score of adherence to the Mediterranean dietary patterns between cases and controls, with mean values of 8.37 +/- 1.80 and 8.25 +/- 2.48, respectively. However, MeDi was associated with lower PCa agressiveness according to Gleason score. Hence, relations between Mediterranean dietary patterns and PCa are still inconclusive and merit further investigations. Further large-scale studies are required to clarify the effect of MeDi on prostate health, in order to establish the role of this diet in the prevention of PCa.