Nanoparticle Size Detection Limits by Single Particle ICP-MS for 40 Elements
Nanoparticle Size Detection Limits by Single Particle ICP-MS for 40 Elements
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DOI：
10.1021/es502422v
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发表时间：
2014-09-02
影响因子：
11.4
通讯作者：
Westerhoff, Paul
中科院分区：
文献类型：
--
作者：
Lee, Sungyun;Bi, Xiangyu;Westerhoff, Paul
对天然、工程和偶然的纳米至微米尺寸颗粒进行量化和表征，有利于评估纳米材料在制造过程中的性能、在环境中的归宿和迁移以及对人类健康的潜在风险。单粒子电感耦合等离子体质谱（spICP-MS）可以灵敏地定量悬浮在水性基质中的金属纳米颗粒的量和尺寸分布。为了准确地获得纳米颗粒的尺寸分布，关键是要知道使用spICP-MS的尺寸检测限（表示为D-min），用于已经或将要合成为工程纳米颗粒的各种元素（除了少数可用的评估元素）。本文描述了一种使用spICP-MS估计尺寸检测限的方法，然后将其应用于由40种不同元素组成的纳米颗粒。计算出的D-min值与文献中可检测到的几种元素的尺寸吻合良好。假设每个纳米颗粒样品由一种元素组成，D-min值在40种元素中变化很大：Ta、U、Ir、Rh、Th、Ce和Hf显示出最低的D-min值，
The quantification and characterization of natural, engineered, and incidental nano- to micro-size particles are beneficial to assessing a nanomaterial's performance in manufacturing, their fate and transport in the environment, and their potential risk to human health. Single particle inductively coupled plasma mass spectrometry (spICP-MS) can sensitively quantify the amount and size distribution of metallic nanoparticles suspended in aqueous matrices. To accurately obtain the nanoparticle size distribution, it is critical to have knowledge of the size detection limit (denoted as D-min) using spICP-MS for a wide range of elements (other than a few available assessed ones) that have been or will be synthesized into engineered nanoparticles. Herein is described a method to estimate the size detection limit using spICP-MS and then apply it to nanoparticles composed of 40 different elements. The calculated D-min values correspond well for a few of the elements with their detectable sizes that are available in the literature. Assuming each nanoparticle sample is composed of one element, D-min values vary substantially among the 40 elements: Ta, U, Ir, Rh, Th, Ce, and Hf showed the lowest D-min values,