The infectious etiology of vasculitis
The infectious etiology of vasculitis
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DOI：
10.1080/08916930802613210
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发表时间：
2009-01-01
期刊：
影响因子：
3.5
通讯作者：
Shoenfeld, Yehuda
中科院分区：
文献类型：
--
作者：
Lidar, Merav;Lipschitz, Noga;Shoenfeld, Yehuda
Infectious agents have been implicated in the etiopathogenesis of various vasculitides via numerous and overlapping mechanisms including direct microbial invasion of endothelial cells, immune complex mediated vessel wall damage and stimulation of autoreactive B and/or T cells through molecular mimicry and superantigens. While the causative role of hepatitis B virus in polyarteritis nodosa and hepatitis C virus in mixed cryoglobulinemia is clearly established, evidence for the association of other infectious agents with vasculitis, including human immunodeficiency virus, parvovirus B19, cytomegalovirus, varicella zoster virus, Staphylococcus aureus, rickettsiaceae, Treponema pallidum and Borrelia burgdorferi, among numerous others, is accumulating. The spectrum of association of infectious agents; bacteria, viruses and parasites, with systemic vasculitides, will be reviewed herewith.
