Nasal architecture: form and flow
Nasal architecture: form and flow
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DOI：
10.1098/rsta.2008.0083
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发表时间：
2008-09-28
期刊：
影响因子：
5
通讯作者：
Tolley, N.
中科院分区：
文献类型：
--
作者：
Doorly, D. J.;Taylor, D. J.;Tolley, N.
目前的方法来模拟鼻腔气流在这项研究中进行了审查，并提出了新的发现。这些新的结果利用改进的计算和实验技术和资源，现在允许关键的动力学特征进行调查，并提供合理的程序，涉及解剖形式的变化。具体而言，研究了单个受试者的气道复制品和简化气道，并与具有明显不同几何形状的另外两个个体的气道复制品进行了比较。程序的特点和比较复杂的鼻气道几何形状首先概述。然后表明，耦合的计算和实验研究，能够获得高分辨率的数据，揭示内在的稳定和非稳定的情况下的内部流结构。结果表明，鼻的形式和流量之间的密切关系，可以探索更详细的比迄今为止可能的。通过概述比较复杂气道几何形状的方法并展示合理的几何简化对流动结构的影响，这项工作为研究自然管道如何引导和控制流动提供了一种新的方法。这些概念和工具解决了其他生理系统中的流量研究所普遍存在的问题。
Current approaches to model nasal air flow are reviewed in this study, and new findings presented. These new results make use of improvements to computational and experimental techniques and resources, which now allow key dynamical features to be investigated, and offer rational procedures to relate variations in anatomical form. Specifically, both replica and simplified airways of a single subject were investigated and compared with the replica airways of two other individuals with overtly differing geometries. Procedures to characterize and compare complex nasal airway geometry are first outlined. It is then shown that coupled computational and experimental studies, capable of obtaining highly resolved data, reveal internal flow structures in both intrinsically steady and unsteady situations. The results presented demonstrate that the intimate relation between nasal form and flow can be explored in greater detail than hitherto possible. By outlining means to compare complex airway geometries and demonstrating the effects of rational geometric simplification on the flow structure, this work offers a fresh approach to studies of how natural conduits guide and control flow. The concepts and tools address issues that are thus generic to flow studies in other physiological systems.