A miniature all-optical photoacoustic imaging probe
A miniature all-optical photoacoustic imaging probe
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DOI：
10.1117/12.874883
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发表时间：
2011-02
期刊：
影响因子：
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通讯作者：
E. Zhang;P. Beard
中科院分区：
文献类型：
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作者：
E. Zhang;P. Beard
研制了一种用于内窥镜的微型光声探头（外径250 μm）。它包括一个单一的传输光纤，在其远端有一个透明的法布里-珀罗（FP）超声传感器。传感器的制造是通过沉积薄膜多层结构实现的，该薄膜多层结构包括夹在一对二向色电介质镜之间的聚合物间隔物到单模光纤的尖端上。对探头的声带宽和灵敏度进行了评价。采用凹面FP干涉腔设计，有效地抑制了腔内多次反射光束的相位色散，实现了极高的声灵敏度。在20 MHz带宽上实现的噪声等效噪声（NEP）为8 Pa。后向模式操作的探头证明通过检测光声信号在各种幻影设计模拟内窥镜应用。侧视探头也展示了说明血管内成像应用的全光学设计。
A miniature (250 μm outer diameter) photoacoustic probe for endoscopic applications has been developed. It comprises a single delivery optical fibre with a transparent Fabry Perot (FP) ultrasound sensor at its distal end. The fabrication of the sensor was achieved by depositing a thin film multilayer structure comprising a polymer spacer sandwiched between a pair of dichroic dielectric mirrors on to the tip of a single mode fiber. The probe was evaluated in terms of its acoustic bandwidth and sensitivity. Ultra high acoustic sensitivity has been achieved with a concave FP interferometer cavity design, which effectively suppresses the phase dispersion of multiple reflected beam within the cavity to achieve high finesse. The noise equivalent noise (NEP) achieved is 8 Pa over a 20 MHz bandwidth. Backward mode operation of the probe is demonstrated by detecting photoacoustic signals in a variety of phantoms designed to simulate endoscopic applications. A side-viewing probe is also demonstrated illustrating an all-optical design for intravascular imaging applications.