National trends in Staphylococcus aureus infection rates:: Impact on economic burden and mortality over a 6-year period (1998-2003)

National trends in Staphylococcus aureus infection rates:: Impact on economic burden and mortality over a 6-year period (1998-2003)
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DOI:
10.1086/522186
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发表时间:
2007-11-01
影响因子:
11.8
通讯作者:
Bharmal, Murtuza
Bharmal, Murtuza
中科院分区:
医学1区
文献类型:
--
作者:
Noskin, Gary A.;Rubin, Robert J.;Bharmal, Murtuza

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背景。我们评估了 1998 年至 2003 年美国医院金黄色葡萄球菌感染率、经济负担和死亡率的历史趋势。方法。全国住院患者样本用于评估 1998 - 2003 年间金黄色葡萄球菌感染随时间变化的趋势。确定了 5 个住院时间层的历史趋势,包括所有住院时间、外科手术时间、侵入性心血管手术时间、侵入性骨科手术时间和侵入性神经外科手术时间。结果。在 1998 年至 2003 年的 6 年研究期间,所有住院患者(从 0.74% 增至 1.0%;年百分比变化 (APC),7.1%;P=.004)、手术住院(从 0.90% 增至 1.3%;APC,7.9%;P=.001)和侵入性骨科患者的金黄色葡萄球菌感染率显着增加。手术停留时间(从 1.2% 降至 1.8%;APC,9.3%;P
Background. We evaluated historical trends in the Staphylococcus aureus infection rate, economic burden, and mortality in US hospitals from 1998 through 2003.Methods. The Nationwide Inpatient Sample was used to assess trends over time of S. aureus infection during 1998 - 2003. Historical trends were determined for 5 strata of hospital stays, including all inpatient stays, surgical procedure stays, invasive cardiovascular surgical stays, invasive orthopedic surgical stays, and invasive neurosurgical stays.Results. During the 6- year study period from 1998 through 2003, the rate of S. aureus infection increased significantly for all inpatient stays (from 0.74% to 1.0%; annual percentage change (APC), 7.1%; P=.004), surgical stays (from 0.90% to 1.3%; APC, 7.9%; P=.001), and invasive orthopedic surgical stays (from 1.2% to 1.8%; APC, 9.3%; P