Efficient route to 4a-methyltetrahydrofluorenes:: A total synthesis of (±)-dichroanal B via intramolecular Heck reaction
Efficient route to 4a-methyltetrahydrofluorenes:: A total synthesis of (±)-dichroanal B via intramolecular Heck reaction
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DOI：
10.1021/jo052454q
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发表时间：
2006-03-31
影响因子：
3.6
通讯作者：
Node, M
中科院分区：
文献类型：
--
作者：
Planas, L;Mogi, M;Node, M
提出了一条基于二烯11分子内Heck环化制备4a-甲基四氢芴二萜类化合物的新途径，并将其用于(+/-)-二氯萘酚B的全合成，总收率显著提高。
An efficient new route based on intramolecular Heck cyclization of the diene 11 was developed to prepare the 4a-methyltetrahydrofluorene diterpenoids and utilized for the total synthesis of (+/-)-dichroanal B with Significantly improved overall yield.