Advances in bio-active constituents, pharmacology and clinical applications of rhubarb.
Advances in bio-active constituents, pharmacology and clinical applications of rhubarb.
复制标题
DOI：
10.1186/s13020-017-0158-5
复制
发表时间：
2017
期刊：
影响因子：
4.9
通讯作者：
Duan JA
中科院分区：
文献类型：
--
作者：
Cao YJ;Pu ZJ;Tang YP;Shen J;Chen YY;Kang A;Zhou GS;Duan JA
大黄是我国最古老、最常用、最重要的中草药之一。大黄的现代研究更科学、更严谨地阐明了其功效、成分和作用机理。大黄的主要化学成分包括蒽醌、蒽酮、二苯乙烯类、单宁、多糖等，这些成分具有广泛的药理活性，包括调节胃肠、抗癌、抗菌、保肝、抗炎、保护心脑血管等。本文就其活性成分、药理作用、临床应用及作用机制等方面的研究进展作一综述。
Rhubarb is one of the most ancient, commonly used and important herbs in Chinese medicine. The modern researches of rhubarb clarified the efficacies, ingredients and mechanisms in a more scientific and rigorous way. The main chemical compositions of rhubarb include anthraquinones, anthrones, stilbenes, tannins, polysaccharides etc. These compositions show extensive pharmacological activities including regulating gastrointestinal, anticancer, antimicrobial, hepatoprotective, anti-inflammatory, protecting cardiovascular, cerebrovascular and so on. This paper reviews the recent studies on the active ingredients, pharmacological effects, clinical application and functional mechanism.