Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
Differential modulation of agonist potency and receptor coupling by mutations of Ser388Tyr and Thr389Pro at the junction of transmembrane domain VI and the third extracellular loop of human M(1) muscarinic acetylcholine receptors.
复制标题
通过跨膜结构域 VI 和人 M(1) 毒蕈碱乙酰胆碱受体第三胞外环连接处的 Ser388Tyr 和 Thr389Pro 突变对激动剂效力和受体偶联进行差异调节。
作者：
Huang,XP;Williams,FE;Peseckis,SM;MesserJr,WS
