Enhanced imaging of choroidal vasculature by high-penetration and dual-velocity optical coherence angiography.
Enhanced imaging of choroidal vasculature by high-penetration and dual-velocity optical coherence angiography.
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DOI：
10.1364/boe.2.001147
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发表时间：
2011-04-11
影响因子：
3.4
通讯作者：
Yasuno Y
中科院分区：
文献类型：
--
作者：
Jaillon F;Makita S;Min EJ;Lee BH;Yasuno Y
双光束扫描多普勒光学相干血管造影术（DB-OCA）与1 μ m波长的探头被证明是改善在体内脉络膜血管造影的人眼。该方法利用两束在视网膜上具有空间和时间分离的扫描光束，并提供两个可测量的速度范围。该方法实现了更高的灵敏度，非常低的速度流比传统的多普勒光学相干层析成像。此外，更长的波长允许更大的穿透，增强脉络膜血管的可视化与多普勒频移平方的正面投影图像验证。具体而言，在1 μm波长处比在840 nm处实现更好的脉络膜脉管系统可见性。
Dual-beam-scan Doppler optical coherence angiography (DB-OCA) with a 1-μm-wavelength probe is demonstrated for improved in vivo choroidal angiograms of the human eye. This method utilizes two scanning beams with spatial and temporal separation on the retina, and provides two measurable velocity ranges. The method achieves higher sensitivity to very low velocity flows than conventional Doppler optical coherence tomography. Moreover, longer wavelengths allowing greater penetration, enhanced visualization of choroidal vessels is verified with en-face projection images of the Doppler shift squared. Specifically, better choroidal vasculature visibility is achieved at a wavelength of 1 μm than at 840 nm.