Two-dimensional metal-organic framework nanosheets as a matrix for laser desorption/ionization of small molecules and monitoring enzymatic reactions at high salt concentrations
Two-dimensional metal-organic framework nanosheets as a matrix for laser desorption/ionization of small molecules and monitoring enzymatic reactions at high salt concentrations
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二维金属有机骨架纳米片作为小分子激光解吸/电离基质并监测高盐浓度下的酶反应
DOI：
10.1039/c6cc07371a
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发表时间：
2016-01-01
影响因子：
4.9
通讯作者：
Gu, Zhi-Yuan
中科院分区：
文献类型：
--
作者：
Liu, Hai-Long;Chang, Yu-Jie;Gu, Zhi-Yuan
利用稳定的2-D金属有机骨架纳米片作为上级清洁背景基质，用于正离子和负离子模式下的小生物分子和污染物的MALDI-TOF MS分析。基质可以不寻常地提供高达1000 mM的盐浓度的神经递质乙酰胆碱的酶水解的监测。
Stable 2-D metal-organic framework nanosheets were utilized as a superior clean-background matrix for MALDI-TOF MS analysis of small biomolecules and pollutants in both positive and negative ion modes. The matrix could unusually afford up to 1000 mM of the salt concentrations in the monitoring of the enzymatic hydrolysis of neurotransmitter acetylcholine.