False Daptomycin-Nonsusceptible MIC Results by Microscan Panel PC 29 Relative to Etest Results for Staphylococcus aureus and Enterococci

False Daptomycin-Nonsusceptible MIC Results by Microscan Panel PC 29 Relative to Etest Results for Staphylococcus aureus and Enterococci
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DOI:
10.1128/jcm.01721-12
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发表时间:
2013-01-01
影响因子:
9.4
通讯作者:
Burnell, Jacqueline M.
Burnell, Jacqueline M.
中科院分区:
医学2区
文献类型:
--
作者:
Palavecino, Elizabeth L.;Burnell, Jacqueline M.

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本研究比较了MicroScan和Etest对金黄色葡萄球菌和肠球菌的达托霉素MIC结果,发现MicroScan面板GP-29具有较高的假不敏感结果。在MicroScan判定为不敏感的菌株中,87%的金黄色葡萄球菌、90%的粪肠球菌和88%的粪肠球菌经ETEST判定为敏感。反过来,与参考方法相比,ETEST也有虚假的不敏感结果。
This study correlated the daptomycin MIC results obtained by Microscan and by Etest in Staphylococcus aureus and enterococci and found that the Microscan panel GP 29 had a high rate of false nonsusceptible results. Of the isolates interpreted as nonsusceptible by Microscan, 87% of Staphylococcus aureus, 90% of Enterococcus faecalis, and 88% of Enterococcus faecium isolates were interpreted as susceptible by Etest. In turn, Etest also has false nonsusceptible results compared to reference methods.