Prevalence of chronic rhinosinusitis in the general population based on sinus radiology and symptomatology
Prevalence of chronic rhinosinusitis in the general population based on sinus radiology and symptomatology
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DOI：
10.1016/j.jaci.2018.12.986
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发表时间：
2019-03-01
影响因子：
14.2
通讯作者：
Fokkens, Wytske J.
中科院分区：
文献类型：
--
作者：
de Loos, Dirk Dietz;Lourijsen, Evelijn S.;Fokkens, Wytske J.
背景：流行病学研究中测量的慢性鼻窦炎（CRS）的患病率为5%至12%。这可能是一个高估，因为重叠与其他疾病，如过敏性鼻炎。目的：我们的目的是计算CRS的流行病学为基础的CRS根据欧洲立场文件对鼻鼻窦炎和鼻息肉（EPOS）连同鼻窦混浊的影像学。方法：要求接受头部计算机断层扫描或磁共振成像扫描的受试者填写全球过敏和哮喘欧洲网络调查，EPOS症状标准。根据Lund-Mackay（LM）评分系统对扫描进行评价。流行病学为基础的CRS是根据鼻症状EPOS;临床为基础的CRS还包括内窥镜和/或CT scanning.Results：八百三十四名受试者。根据EPOS，107例（12.8%）有流行病学基础的CRS。在这些受试者中，50%的LM评分为0，26%的LM评分为1 - 3，23%的LM评分为4或更高。25例（3.0%）受试者有临床CRS（基于LM评分>= 4），53例（6.4%）受试者有临床CRS（基于LM评分> 0）。167例（20%）受试者报告了过敏性鼻炎。在未报告上呼吸道症状的受试者中，57%的LM评分为0，30%的LM评分为1 - 3，12%的LM评分为4或更高。（取决于LM截止点;即，分别为LM > 4或LM > 0）。
Background: The prevalence of chronic rhinosinusitis (CRS) measured in epidemiologic studies is 5% to 12%. This might be an overestimation because of overlap with other diseases, such as allergic rhinitis.Objective: We aimed to calculate the prevalence of CRS using a combination of epidemiologically based CRS according to the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS) together with sinonasal opacification on imaging.Methods: Subjects who underwent a computed tomographic or magnetic resonance imaging scan of the head for any nonrhinologic indication were asked to fill in the Global Allergy and Asthma European Network survey containing EPOS symptom criteria. The scans were evaluated according to the Lund-Mackay (LM) scoring system. Epidemiologically based CRS is based on nasal symptoms according to EPOS; clinically based CRS also encompasses endoscopy and/or CT scanning.Results: Eight hundred thirty-four subjects were included. One hundred seven (12.8%) had epidemiologically based CRS according to EPOS. Of these subjects, 50% had an LM score of 0, 26% had an LM score of 1 to 3, and 23% had an LM score of 4 or greater. Twenty-five (3.0%) subjects had clinically based CRS (based on LM score >= 4), and 53 (6.4%) subjects had clinically based CRS (based on LM score > 0). Allergic rhinitis was reported by 167 (20%) subjects. In subjects who did not report upper airway symptoms, 57% had an LM score of 0, 30% had an LM score of 1 to 3, and 12% had an LM score of 4 or greater.Conclusion: We found a prevalence of 3.0% to 6.4% of clinically based CRS (depending on an LM cutoff point; ie, LM > 4 or LM > 0, respectively) in a relatively randomly selected group of subjects.