2-O-Alkylated para-benzamide α-helix mimetics: the role of scaffold curvature
2-O-Alkylated para-benzamide α-helix mimetics: the role of scaffold curvature
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DOI：
10.1039/c2ob26262b
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发表时间：
2012-01-01
影响因子：
3.2
通讯作者：
Wilson, Andrew J.
中科院分区：
文献类型：
--
作者：
Azzarito, Valeria;Prabhakaran, Panchami;Wilson, Andrew J.
设计并合成了一种新的2-O-烷基化苯甲酰胺α-螺旋模拟物。与区域异构3-O-烷基化苯甲酰胺的比较允许的作用，模拟曲率在确定分子识别性能的初步评价。
The design and synthesis of a new 2-O-alklyated benzamide alpha-helix mimetic is described. Comparison with regioisomeric 3-O-alkylated benzamides permits a preliminary evaluation of the role that mimetic curvature has in determining molecular recognition properties.