Transplantation rate of the blood group B waiting list is increased by using A2 and A2B kidneys
Transplantation rate of the blood group B waiting list is increased by using A2 and A2B kidneys
复制标题
DOI：
10.1097/00007890-199812270-00025
复制
发表时间：
1998-12-27
期刊：
影响因子：
6.2
通讯作者：
Harrell, KM
中科院分区：
文献类型：
--
作者：
Bryan, CF;Shield, CF;Harrell, KM
背景我们通过移植A（2）和A（2）B型肾，提高了等待名单中的B血型候选人的移植率。自1991年以来，在我们器官采购组织服务区的7个肾移植项目中，有5个优先将A（2）和A（2）B血型尸体肾移植给有低抗A同种凝集素滴度病史的B血型等待名单候选人。在1991年至1997年期间，这五个中心对71名来自B尸体的患者进行了移植：等待名单。在这71例患者中，29%（21/71）接受了A（2）（n = 18）或A（2）B（n = 3）尸体肾移植。仅在1997年，48%（11/23）的B患者移植受体接受了A或A（2）B肾。将A（2）和A（2）B肾移植到等待名单上的B患者中成功地增加了B患者获得肾脏的机会。这种在全国范围内实施的分配算法可以类似地增加B等待名单候选人的移植率。
Background. We have increased the transplantation rate for blood group B cadaveric waiting list candidates by transplanting them with A(2) and A(2)B kidneys.Methods. Since 1991, five of the seven renal transplant programs in our organ procurement organization service area have preferentially transplanted blood group A(2) and A(2)B cadaveric kidneys to B blood group waiting list candidates with histories of low anti-A isoagglutinin titers.Results. Between 1991 and 1997, these five centers performed transplantations on 71 patients from the B cadaveric: waiting list. Of those 71 patients, 29% (21 of 71) underwent transplantation with either A(2) (n = 18) or A(2)B (n = 3) cadaveric kidneys. In 1997 alone, 48% (11 of 23) of the B patient transplant recipients received A,or A(2)B kidneys.Conclusions. Transplantation of A(2) and A(2)B kidneys into B waiting list patients has successfully increased access of B patients to kidneys. Such an allocation algorithm implemented nationally may similarly increase the transplantation rate of B waiting list candidates.