[A case of alpha-fetoprotein producing embryonal carcinoma of the stomach].
[A case of alpha-fetoprotein producing embryonal carcinoma of the stomach].
复制标题
产甲胎蛋白胃胚胎癌1例[J].
DOI：
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
M. Kaji
中科院分区：
文献类型：
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作者：
T. Yano;U. Miyamoto;T. Mukai;K. Noda;Y. Eto;T. Uchida;I. Oya;M. Kaji
A 67-year-old man with complaints of general malaise and epigastralgia was admitted to our hospital for further examination. Upper GI series and endoscopy showed advanced cancer, Borrmann type II; biopsy specimens revealed pathological pictures of malignancy. The serum alpha-fetoprotein values were remarkably high (473,000 ng/dl); the liver scintigram revealed a space-occupying lesion in the right lobe and the abdominal CT-scan showed ascites and lymphadenopathy of the abdominal para-aortic region. Therefore, double cancer of the stomach and the liver was suspected. The patient died in a state of hepatic coma with a rapid increase of jaundice, ascites and right pleural effusion at 3 weeks after admission despite the anti-cancer treatment. Autopsy revealed embryonal carcinoma with yolk sac tumor elements of stomach origin, extensive metastasis to the liver, lung, peritoneum, and portal vein. The peroxidase anti-peroxidase technique revealed that primary and secondary tumor cells produced alpha-fetoprotein.
