Intragenomic conflict over queen determination favours genomic imprinting in eusocial Hymenoptera
Intragenomic conflict over queen determination favours genomic imprinting in eusocial Hymenoptera
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蜂王决定的基因组内冲突有利于真社会性膜翅目基因组印记
DOI：
10.1098/rspb.2011.2673
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Tsuji K
中科院分区：
文献类型：
--
作者：
Dobata S;Tsuji K
由于群体成员之间的密切相互作用和单倍体的亲缘不对称所引起的进化冲突，诸如蚂蚁、蜜蜂和黄蜂等群居膜翅目昆虫一直被认为是基因组印记研究的候选者。尽管基因组印记的一般亲缘关系理论预测了它在群体生命周期的各种情况下的发生，但基于对蚂蚁和蜜蜂的分子水平理解的最新进展，需要新的理论方法来解释真实群体的具体情况。使用多变量定量遗传模型，我们研究了基因组印记对决定携带雌虫发育为皇后种姓倾向的基因的潜在影响。当蜂王由于倾向增加而产生的生产过剩以群体为代价时，在多雄制（蜂王多次交配）的群体中，母系和父系遗传基因之间的冲突有利于基因组印记。此外，我们表明，一旦纳入新雄性和新女王所经历的成本差异，即使在一妻制（女王单次交配）下，基因组印记也可能发生。我们的模型预测在一妻多夫的蚁群中存在着父系特异性表达的“遗传欺骗”，这似乎与一妻多夫的阿根廷蚂蚁中父系对蚁后决定的影响是一致的。
Colonies of eusocial Hymenoptera, such as ants, bees and wasps, have long been recognized as candidates for the study of genomic imprinting on the grounds of evolutionary conflicts that arise from close interactions among colony members and relatedness asymmetry owing to haplodiploidy. Although a general kinship theory of genomic imprinting predicts its occurrence under various circumstances of the colony life cycle, new theoretical approaches are required to account for the specifics of real colonies based on recent advances in molecular-level understanding of ants and honeybees. Using a multivariate quantitative genetic model, we examined the potential impact of genomic imprinting on genes that determine the carrier female's propensity to develop into the queen caste. When queen overproduction owing to the increased propensity comes at a colony-level cost, the conflict between maternally and paternally inherited genes in polyandrous (queen multiple mating) colonies favours genomic imprinting. Moreover, we show that the genomic imprinting can occur even under monandry (queen single mating), once incorporating the costs differentially experienced by new males and new queens. Our model predicts the existence of imprinted ‘genetic royal cheats’ with patriline-specific expression in polyandrous colonies, and seems consistent with the paternal effect on queen determination in monandrous Argentine ants.