Relation between bone mineral content and clinical, hormonal and biochemical parameters in postmenopausal women

Relation between bone mineral content and clinical, hormonal and biochemical parameters in postmenopausal women
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绝经后妇女骨矿物质含量与临床、激素和生化参数的关系

DOI:
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发表时间:
1998
影响因子:
2.6
通讯作者:
A. Mumcu
A. Mumcu
中科院分区:
医学3区
文献类型:
--
作者:
B. Acar;T. Uslu;A. Topuz;E. Osma;T. Erçal;C. Posacı;Y. Erata;A. Mumcu

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摘要。我们研究了73名在某大学医院更年期门诊就诊的健康女性自然或手术绝经后骨量的相关因素。在自然绝经组中,我们发现骨密度(BMD)与绝经时间呈负相关;骨密度与身体质量指数(BMI)、BMI与无机磷酸盐(Pi)、体重与甲状腺素(T4)、体重与黄体生成素(LH)之间的临界相关性以及雄烯二酮(D4A)与尿钙(Uca)之间的正相关性。在手术绝经组中,我们发现了一些负相关(骨密度与绝经时间、BMI与Pi、BMI与脱氢表雄酮硫酸盐(DS)、体重与DS、皮质醇与Uca)和一些正相关(骨密度与游离睾酮(fT)、骨密度与钙(Ca)、骨密度与Uca)。我们的结论是,我们测量的血清激素水平不是当前骨矿物质状态的有用标记。
Abstract. We studied factors related to bone mass after a natural or surgical menopause in 73 healthy women attending the menopause clinic of a university hospital. In the natural menopause group we found inverse correlations between bone mineral density (BMD) vs. menopausal duration; BMD vs. body mass index (BMI) and BMI vs. inorganic phosphate (Pi), borderline correlations between weight vs. thyroxin (T4) and weight vs. luteinising hormone (LH) and a positive correlation between androstenedione (D4A) vs. urinary calcium (Uca). In the surgical menopause group we found some negative correlations (BMD vs. menopausal duration, BMI vs. Pi; BMI vs. dehydroepiandrosterone sulphate (DS), weight vs. DS and cortisol vs. Uca) and some positive correlations (BMD vs. free testosterone (fT), BMD vs. calcium (Ca), and BMD vs. Uca). We concluded that the serum hormone levels we measured were not useful markers of current bone mineral status.
一种潜在的灵长类动物模型,用于治疗因医学卵巢切除术或绝经而导致的骨质流失。
DOI: 10.1210/jcem-71-1-105
发表时间: 1990
期刊: The Journal of clinical endocrinology and metabolism
影响因子: --
作者:
Mann,DR;Gould,KG;Collins,DC
通讯作者: Collins,DC
根据之前使用口服避孕药确定的绝经后妇女的骨矿物质密度。
DOI: 10.2105/ajph.83.1.100
发表时间: 1993
影响因子: 12.7
作者:
Kritz-Silverstein,D;Barrett-Connor,E
通讯作者: Barrett-Connor,E