Sleep Patterns in Adults with a Diagnosis of High-Functioning Autism Spectrum Disorder
Sleep Patterns in Adults with a Diagnosis of High-Functioning Autism Spectrum Disorder
复制标题
DOI：
10.5665/sleep.5160
复制
发表时间：
2015-11-01
期刊：
影响因子：
5.6
通讯作者：
Richdale, Amanda L.
中科院分区：
文献类型：
--
作者：
Baker, Emma K.;Richdale, Amanda L.
研究目的：研究诊断为自闭症谱系障碍且无共病智力残疾的成年人的睡眠模式和睡眠问题及其与日间功能的关系（高功能自闭症谱系障碍[HFASD]）与神经型（NT）成人相比。设计：横断面。设置：家庭为基础的研究。参与者：36名HFASD成人和36名年龄、智力和性别匹配的NT成人。测量：参与者完成了一系列在线问卷调查，包括匹兹堡睡眠质量指数（PSQI）、14天睡眠觉醒日记和14天活动记录数据收集。HFASD成人患者的一般睡眠障碍明显更多，PSQI评分更高，睡眠起始时间更长，（活动记录）和较差的睡眠效率（日记），这些结果在考虑错误发现率后仍然显著。与NT成人相比，那些没有焦虑/抑郁共病诊断的HFASD成人的总睡眠时间（日记和活动记录）显著缩短。与NT成人相比，HFASD组自我报告显着较差的刷新分数醒来后，在早上和较高的分数，白天功能障碍，由于嗜睡子量表的PSQI.Conclusions：这些研究结果支持的概念，睡眠相关的问题，特别是失眠，持续到成年期的个人与高功能自闭症谱系障碍。
Study Objectives: To examine sleep patterns and sleep problems and their relationship with daytime functioning in adults with a diagnosis of an autism spectrum disorder and no comorbid intellectual disability (high-functioning autism spectrum disorder [HFASD]) compared to neurotypical (NT) adults.Design: Cross-sectional.Setting: Home-based study.Participants: 36 adults with HFASD and 36 age-, intelligence quotient-and sex-matched NT adults.Measurements: Participants completed an online questionnaire battery including the Pittsburgh Sleep Quality Index (PSQI), a 14-d sleep wake diary and 14-d actigraphy data collection.Results: Adults with HFASD had significantly more general sleep disturbances and higher scores on the PSQI, longer sleep onset latencies (actigraphy), and poorer sleep efficiency (diary) and these results remained significant after accounting for the False Discovery Rate. Those adults with HFASD who did not have a comorbid diagnosis of anxiety/depression had significantly shorter total sleep time (diary and actigraphy) compared to NT adults. Compared to NT adults, the HFASD group self-reported significantly poorer refreshment scores upon waking in the morning and higher scores on the daytime dysfunction due to sleepiness subscale of the PSQI.Conclusions: These findings support the notion that problems related to sleep, in particular insomnia, continue into adulthood in individuals with high-functioning autism spectrum disorder.