AUTOIMMUNITY IN CHRONIC LYMPHOCYTIC-LEUKEMIA
AUTOIMMUNITY IN CHRONIC LYMPHOCYTIC-LEUKEMIA
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DOI：
10.1136/jcp.39.7.713
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发表时间：
1986-07-01
影响因子：
3.4
通讯作者：
YOUNG, BJ
中科院分区：
文献类型：
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作者：
HAMBLIN, TJ;OSCIER, DG;YOUNG, BJ
研究了B细胞慢性淋巴细胞白血病（B- cll）自身抗体的流行情况。发现自身免疫性溶血性贫血的患病率低于其他系列：大量非进展期。包括1例疾病病例，其中自身免疫性溶血性贫血患病率较低。非血液学自身抗体并不比年龄匹配的对照组常见。无论对B-CLL的自身免疫现象给出何种解释，都必须考虑到这样一个事实，即这些现象实际上仅限于针对血液中形成元素的自身抗体。
The prevalence of autoantibodies in B cell chronic lymphocytic leukaemia (B-CLL) was investigated. A lower prevalence of autoimmune haemolytic anaemia than that found in other series was found: large numbers of non-progressive stage. A disease cases were included, in which the prevalence of autoimmune haemolytic anaemia is low. Non-haematological autoantibodies were no commoner than in age matched controls. Whatever explanation is offered for autoimmune phenomena in B-CLL it must take account of the fact that those phenomena are virtually confined to autoantibodies against the formed elements of the blood.