Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy
Modified moving average analysis of T-wave alternans to predict ventricular fibrillation with high accuracy
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DOI：
10.1152/japplphysiol.00592.2001
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发表时间：
2002-02-01
影响因子：
3.3
通讯作者：
Verrier, RL
中科院分区：
文献类型：
--
作者：
Nearing, BD;Verrier, RL
T波电交替是心脏电不稳定的标志，具有心律失常风险分层的潜力。改进的移动平均法被开发用于测量具有伪影、噪声和非平稳数据的设置中的交替。开发了算法，并使用模拟心电图（ECG）验证了性能特征。实验室心电图与动态变化交替值进行了分析。通过改进的移动平均分析估计的交替值与输入交替值强烈相关（r（2）= 0.9999）。快速变化的交替水平和相位反转没有干扰测量。当心率从60次/分增加到180次/分，T波交替峰从R波后237 ms移动到103 ms时，测量的交替峰发生变化
T-wave alternans is a marker of cardiac electrical instability with the potential for arrhythmia risk stratification. The modified moving average method was developed to measure alternans in settings with artifacts, noise, and nonstationary data. Algorithms were developed and performance characteristics were validated with simulated electrocardiograms (ECGs). Experimental laboratory ECGs with dynamically changing alternans values were analyzed. Alternans values estimated by modified moving average analysis correlated strongly with input alternans values (r(2) = 0.9999). Rapidly changing alternans levels and phase reversals did not perturb the measurement. When heart rate was increased from 60 to 180 beats/min, with T-wave alternans apex moving from 237 to 103 ms after the R wave, the measured alternans peak varied