Dissociation of visual, motor and predictive signals in parietal cortex during visual guidance
Dissociation of visual, motor and predictive signals in parietal cortex during visual guidance
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DOI：
10.1038/4594
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发表时间：
1999-01-01
影响因子：
25
通讯作者：
Assad, JA
中科院分区：
文献类型：
--
作者：
Eskandar, EN;Assad, JA
研究了后顶叶皮层（PPC）在运动视觉引导中的作用，猴子被训练使用操纵杆引导一个点到一个目标。视觉和运动的影响被分离的瞬时闭塞点，并通过改变操纵杆的方向和现场运动之间的关系。我们发现在视觉引导过程中PPC的功能有很强的分离。MST区的神经元受到可见移动刺激方向的选择性调制，而MIP区的神经元受到手运动方向的选择性调制。与此相反，在外侧顶内区（LIP）的细胞的选择性并不直接依赖于视觉输入或运动输出，而是似乎编码一个预测表示的刺激运动。这些预测信号可能是视觉转换中的重要环节。
The role of the posterior parietal cortex (PPC) in the visual guidance of movements was studied in monkeys trained to use a joystick to guide a spot to a target. Visual and motor influences were dissociated by transiently occluding the spot and by varying the relationship between the direction of joystick and spot movements. We found a strong segregation of function in PPC during visual guidance. Neurons in area MST were selectively modulated by the direction of visible moving stimuli, whereas neurons in area MIP were selectively modulated by the direction of hand movement. In contrast, the selectivity of cells in the lateral intraparietal area (LIP) did not directly depend on either visual input or motor output, but rather seemed to encode a predictive representation of stimulus movement. These predictive signals may be an important link in visuomotor transformations.