The role of starburst amacrine cells in visual signal processing.
The role of starburst amacrine cells in visual signal processing.
复制标题
星爆无长突细胞在视觉信号处理中的作用。
DOI：
10.1017/s0952523811000393
复制
发表时间：
2012
影响因子：
1.9
通讯作者：
Smith,RG
中科院分区：
文献类型：
--
作者：
Taylor,WR;Smith,RG
Starburst amacrine cells (SBACs) within the adult mammalian retina provide the critical inhibition that underlies the receptive field properties of direction-selective ganglion cells (DSGCs). The SBACs generate direction-selective output of GABA that differentially inhibits the DSGCs. We review the biophysical mechanisms that produce directional GABA release from SBACs and test a network model that predicts the effects of reciprocal inhibition between adjacent SBACs. The results of the model simulations suggest that reciprocal inhibitory connections between closely spaced SBACs should be spatially selective, while connections between more widely spaced cells could be indiscriminate. SBACs were initially identified as cholinergic neurons and were subsequently shown to contain release both acetylcholine and GABA. While the role of the GABAergic transmission is well established, the role of the cholinergic transmission remains unclear.
