Facilitators and Barriers to Uptake of the Med Safety Mobile App for Adverse Drug Reaction Reporting by Health Workers in Uganda: A Qualitative Study.

Facilitators and Barriers to Uptake of the Med Safety Mobile App for Adverse Drug Reaction Reporting by Health Workers in Uganda: A Qualitative Study.
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DOI:
10.1007/s40264-023-01303-6
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发表时间:
2023-06
期刊:
影响因子:
4.2
通讯作者:
Pirmohamed, Munir
Pirmohamed, Munir
中科院分区:
医学2区
文献类型:
--
作者:
Kiguba, Ronald;Zakumumpa, Henry;Ndagije, Helen B.;Mwebaza, Norah;Ssenyonga, Ronald;Tregunno, Phil;Harrison, Kendal;Pirmohamed, Munir

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药物不良反应(ADR)是全球范围内的一项重要公共卫生挑战;然而,药物警戒系统受到报告不足的困扰。移动的技术,包括Med Safety等移动的应用程序,可以加强ADR报告。我们探讨了乌干达卫生工作者对药品不良反应报告的可接受性和可能影响药品安全性的因素。该研究于2020年7月至9月在乌干达的12家艾滋病诊所进行,采用了定性探索性研究设计。我们进行了22次深入访谈和3个混合性别的焦点小组讨论(49名参与者)与各种各样的卫生工作者。我们使用主题方法分析数据。卫生工作者有意愿采用Med Safety进行ADR报告,大多数人会向其他卫生工作者推荐该应用程序。实践培训提高了应用程序的可接受性。应用程序的使用受到以下人群的青睐:年轻、技术熟练的卫生工作者;应用程序的离线和双向风险沟通功能;一些卫生机构提供免费互联网热点;卫生工作者报告ADR的善意和意愿;以及传统ADR报告工具的繁琐性。采用Med Safety的潜在障碍是在ADR报告期间初始应用程序注册和完成多个屏幕的漫长过程;卫生工作者智能手机的挑战(与应用程序不兼容,没有更多应用程序的空间,电池电量低);互联网数据成本高;互联网连接不良;难以识别ADR,语言障碍和对ADR报告者的反馈差。卫生工作者有意愿采用Med Safety进行ADR报告,大多数人会向其他卫生工作者推荐该应用程序。实践培训提高了应用程序的可接受性,并应成为未来所有应用程序推广活动的组成部分。确定的促进因素和障碍可用于适当指导未来的研究和实施,以促进中低收入国家采用Med Safety进行药物警戒。在线版本包含补充材料,可通过10.1007/s40264-023-01303-6获得。
Adverse drug reactions (ADRs) are an important public health challenge worldwide; however, pharmacovigilance systems are plagued by under-reporting. Mobile technologies, including mobile applications such as Med Safety, could strengthen ADR reporting. We explored the acceptability, and factors that could influence uptake of, Med Safety for ADR reporting by health workers in Uganda. The study took place between July and September 2020 in 12 HIV clinics in Uganda and employed a qualitative exploratory research design. We conducted 22 in-depth interviews and 3 mixed-gender focus group discussions (49 participants) with a diverse range of health workers. We analysed the data using a thematic approach. There was goodwill among the health workers to adopt Med Safety for ADR reporting and the majority would recommend the app to other health workers. Training with practice increased acceptability of the app. Uptake of the app was favoured by the younger, technology proficient, health worker demographic; the app's offline and two-way risk communication functionalities; availability of free internet hotspots at some health facilities; goodwill and willingness of health workers to report ADRs; and the cumbersome nature of conventional ADR reporting tools. Potential barriers to the uptake of Med Safety were the perceived lengthy processes of initial app registration and completion of multiple screens during ADR reporting; challenges with health workers’ smartphones (incompatibility with application, no space for more applications, low battery charge); high cost of internet data; poor internet connectivity; difficulty in recognising ADRs, language barrier and poor feedback to ADR reporters. There was goodwill among the health workers to adopt Med Safety for ADR reporting and the majority would recommend the app to other health workers. Training with practice increased acceptability of the app and should be integral in all future app roll-out campaigns. The identified facilitators and barriers could be used to appropriately guide future research and implementation to promote the uptake of Med Safety for pharmacovigilance in low- and middle-income countries. The online version contains supplementary material available at 10.1007/s40264-023-01303-6.
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