Multipoint Lock-and-Key Assembly of Particles with Anisotropic Dents toward Modeling Rigid Macromolecules in a Colloidal Scale
Multipoint Lock-and-Key Assembly of Particles with Anisotropic Dents toward Modeling Rigid Macromolecules in a Colloidal Scale
复制标题
具有各向异性凹痕的颗粒的多点锁钥匙组装，用于模拟胶体尺度的刚性大分子
DOI：
10.1021/acs.langmuir.1c01163
复制
发表时间：
2021
期刊：
影响因子：
3.9
通讯作者：
Nagao Daisuke
中科院分区：
文献类型：
--
作者：
Watanabe Kanako;Shimura Takuya;Nagasawa Akira;Nagao Daisuke
提出了一种适用于胶体建模的多点锁键粒子组合方法，该方法由具有多个各向异性凹痕的锁粒子和杆状粒子作为键粒子组成。锁微粒在耗尽剂存在的情况下，在键微粒处相互连接，形成模仿刚性聚合物的刚性胶体分子（例如，含有芳环和分子内氢键的聚合物）。单粒子水平的观察，以可视化胶体聚合的粒子组装。光学显微镜观察的锁粒子运动轨迹表明，当锁粒子与另一个锁粒子连接时，粒子的扩散率显著降低，表明粒子组装的形成抑制了粒子的扩散。由于胶体聚合的动力学和区域选择性被认为类似于原子尺度上的聚合，因此所提出的锁-钥匙组装可以成为与微布朗运动相关的原子尺度聚合物的有前途的胶体模型。
Multipoint lock-and-key particle assembly, consisting of lock particles with multiple anisotropic dents and rod-shaped particles as key particles, is developed for colloidal modeling application. The lock particles were connected with each other at a key particle as their joint in the presence of depletants, forming rigid colloidal molecules imitating rigid polymers (e.g., polymers containing aromatic rings and intramolecular hydrogen bonds). A single-particle level observation was conducted to visualize the colloidal polymerization of the particle assembly. Motion trajectories of the lock particles observed by optical microscopy indicated that the particle diffusivity was dramatically lowered when the lock particle connected with another one, suggesting that particle diffusion was suppressed by particle assembly formation. Because the kinetic and regioselectivity of colloidal polymerization are assumed to be analogous to those at the atomic scale, the proposed lock-and-key assembly can be a promising colloidal model for atomic-scale polymers associated with their micro-Brownian motion.