The CLIPMERGE PGx Program: clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics.

The CLIPMERGE PGx Program: clinical implementation of personalized medicine through electronic health records and genomics-pharmacogenomics.
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DOI:
10.1038/clpt.2013.72
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发表时间:
2013-08
影响因子:
6.7
通讯作者:
--
中科院分区:
医学2区
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--
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在过去的十年中,基因组学研究的指数增长已经产生了越来越多的与药物反应相关的序列变异,这些变异可能具有临床实用性。尽管存在障碍,但人们的注意力正转向将这些数据整合到临床护理中的策略。CLIPMERGE PGx计划正在建立一个最佳实践基础设施,用于实施基因组知情处方,使用生物库衍生的临床队列,抢先基因检测和通过电子健康记录部署的真实的实时临床决策支持。临床药理学与治疗学(2013);942,214-217。doi:10.1038/clpt.2013.72
The exponential rise in genomics research over the past decade has yielded a growing number of sequence variants associated with medication response that may have clinical utility. Despite existing barriers, attention is turning to strategies that integrate these data into clinical care. The CLIPMERGE PGx Program is establishing a best‐practices infrastructure for the implementation of genome‐informed prescribing using a biobank‐derived clinical cohort, preemptive genetic testing, and real‐time clinical decision support deployed through the electronic health record.Clinical Pharmacology & Therapeutics(2013);942, 214–217. doi:10.1038/clpt.2013.72
DOI: 10.1197/jamia.m2334
发表时间: 2007-03-01
影响因子: 6.4
作者:
Osheroff, Jerome A.;Teich, Jonathan M.;Detmer, Don E.
通讯作者: Detmer, Don E.
DOI: 10.1038/clpt.2010.279
发表时间: 2011-03
影响因子: 6.7
作者:
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DOI: 10.1097/gim.0b013e318238b38c
发表时间: 2011-12
期刊: Genetics in medicine : official journal of the American College of Medical Genetics
影响因子: --
作者:
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通讯作者: Scott SA