A Power-Efficient Wireless System With Adaptive Supply Control for Deep Brain Stimulation.
A Power-Efficient Wireless System With Adaptive Supply Control for Deep Brain Stimulation.
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DOI：
10.1109/jssc.2013.2266862
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发表时间：
2013-09
影响因子：
5.4
通讯作者：
Ghovanloo M
中科院分区：
文献类型：
--
作者：
Lee HM;Park H;Ghovanloo M
提出了一种用于头戴式脑深部电刺激器（DBS）的节能无线刺激系统。一种新的自适应整流器利用相位控制反馈从恒定的AC功率载波产生可变的DC电源电压，同时通过有源同步开关实现高的AC-DC功率转换效率（PCE）。电流控制刺激器采用闭环电源控制，通过电压读出通道检测刺激部位电位，自动调节刺激顺应电压，提高刺激效率。刺激器还利用闭环主动电荷平衡来将每个部位处的剩余电荷维持在安全限度内，同时从幅移键控功率载波无线接收刺激参数。采用0.5 μ m3 M2 P标准CMOS工艺制作了4路无线电刺激系统样机，占用面积2.25 mm²。在2 MHz的5V峰值交流输入下，自适应整流器在2.8mA负载下提供2.5V ~ 4.6V的可调直流输出，实测PCE为72 ~ 87%。自适应电源控制将刺激效率提高到30%，比固定电源电压提高到58 ~ 68%。无线电刺激系统的原型在体外进行了验证。
A power-efficient wireless stimulating system for a head-mounted deep brain stimulator (DBS) is presented. A new adaptive rectifier generates a variable DC supply voltage from a constant AC power carrier utilizing phase control feedback, while achieving high AC-DC power conversion efficiency (PCE) through active synchronous switching. A current-controlled stimulator adopts closed-loop supply control to automatically adjust the stimulation compliance voltage by detecting stimulation site potentials through a voltage readout channel, and improve the stimulation efficiency. The stimulator also utilizes closed-loop active charge balancing to maintain the residual charge at each site within a safe limit, while receiving the stimulation parameters wirelessly from the amplitude-shift-keyed power carrier. A 4-ch wireless stimulating system prototype was fabricated in a 0.5-μm 3M2P standard CMOS process, occupying 2.25 mm². With 5 V peak AC input at 2 MHz, the adaptive rectifier provides an adjustable DC output between 2.5 V and 4.6 V at 2.8 mA loading, resulting in measured PCE of 72 ~ 87%. The adaptive supply control increases the stimulation efficiency up to 30% higher than a fixed supply voltage to 58 ~ 68%. The prototype wireless stimulating system was verified in vitro.