Efficient elimination of sulfadiazine in an anaerobic denitrifying circumstance: Biodegradation characteristics, biotoxicity removal and microbial community analysis.
Efficient elimination of sulfadiazine in an anaerobic denitrifying circumstance: Biodegradation characteristics, biotoxicity removal and microbial community analysis.
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DOI：
10.1016/j.chemosphere.2020.126472
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发表时间：
2020-03
期刊：
影响因子：
8.8
通讯作者：
Jierong Zheng;Sufang Wang;Aijuan Zhou;Bowei Zhao;Jing Dong;Xiaochan Zhao;Peirui Li;Xiuping Yue
中科院分区：
文献类型：
--
作者：
Jierong Zheng;Sufang Wang;Aijuan Zhou;Bowei Zhao;Jing Dong;Xiaochan Zhao;Peirui Li;Xiuping Yue
磺胺嘧啶（SDZ）作为抗菌剂广泛应用于临床治疗、畜牧业和水产养殖，造成环境风险。本工作首次通过批量实验研究了SDZ在硝酸盐厌氧反硝化系统中的生物降解特性和反应机理。结果表明，初始浓度为50 mg L−1的SDZ在70 h后被降解98.52%，表明厌氧反硝化系统中SDZ的去除效率比厌氧系统提高了55.27%。此外，LC-MS-MS 分析证实，SDZ 可以通过包含 6 个不同反应的 3 条主要降解途径降解为 16 种副产物。通过对反应器微生物群落分析发现，脱硝菌和脱硫菌Desulforhabdus、Ignavibacter、SBR1031_norank、Nocardioides等与系统中SDZ的去除高度相关。废水的生物毒性测试表明，废水中剩余的有机物和无机物可以为大肠杆菌提供营养。 coliand 促进其生长。也就是说，厌氧反硝化系统高效、简单、环境友好，在磺酰胺类抗生素的生物降解方面具有广阔的前景。
Sulfadiazine (SDZ) is widely used in clinical treatment, livestock husbandry and aquaculture as an antibacterial agent, resulting in environmental risks. In this work, batch experiments were conducted to investigate the characteristics of SDZ biodegradation and reaction mechanisms in a nitrate anaerobic denitrifying system for the first time. The results showed that 98.52% of the SDZ, which had an initial concentration of 50 mg L−1, was degraded after 70 h, indicating that the removal efficiency of SDZ in anaerobic denitrifying system was 55.27% higher than that in anaerobic system. Furthermore, LC-MS-MS analysis confirmed that SDZ could be degraded into 16 byproducts via 3 main degradation pathways that contained 6 different reactions. After analyzing the microbial communities of the reactor, the denitrifying bacteria and desulfurizing bacteriaDesulforhabdus,Ignavibacterium,SBR1031_norank,Nocardioides, etc. were highly associated with the removal of SDZ in the system. The biological toxicity test of the effluent indicated that the remaining organic matter and inorganic matter of the effluent could provide nutrients forE. coliand promote its growth. In other words, anaerobic denitrifying systems are highly efficient, simple and environmentally friendly, and have an impressive prospect in the biodegradation of sulfonamide antibiotics.