Oxidative 1,2-difunctionalization of activated alkenes with benzylic C(sp3)-H bonds and aryl C(sp2)-H bonds
Oxidative 1,2-difunctionalization of activated alkenes with benzylic C(sp3)-H bonds and aryl C(sp2)-H bonds
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DOI：
10.1039/c3cc45861j
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发表时间：
2013-01-01
影响因子：
4.9
通讯作者：
Li, Jin-Heng
中科院分区：
文献类型：
--
作者：
Zhou, Ming-Bo;Wang, Cheng-Yong;Li, Jin-Heng
利用DTBP(二叔丁基过氧化氢)通过芳基C(sp(2))-H键和苄基C(sp(3))-H键催化活性烯烃的氧化1，2-二官能化反应，合成官能化氧吲哚。该反应是路易斯酸促进的烯烃双官能化反应的一种新的有机取代策略。
DTBP (di-tert-butyl peroxide) is utilized to mediate oxidative 1,2-difunctionalization of activated alkenes with an aryl C(sp(2))-H bond and a benzylic C(sp(3))-H bond for the synthesis of functionalized oxindoles. This reaction is a new organomediated strategy for alkene difunctionalization facilitated by Lewis acids.