Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms
Effects of the tea catechin epigallocatechin gallate on Porphyromonas gingivalis biofilms
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DOI：
10.1111/jam.12458
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发表时间：
2014-05-01
影响因子：
4
通讯作者：
Ebisu, S.
中科院分区：
文献类型：
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作者：
Asahi, Y.;Noiri, Y.;Ebisu, S.
目的探讨儿茶素没食子儿茶素没食子酸酯（EGCg）对牙周病主要致病菌牙龈卟啉单胞菌（Porphyromonas gingivalis）生物膜形成的影响。方法和结果使用三磷酸腺苷（ATP）生物发光测量生物膜细胞存活。EGCg存在时，已形成生物膜的细胞内ATP水平较对照组显著降低（P
Aims The aim of this study was to investigate the effects of tea catechin epigallocatechin gallate (EGCg) on established biofilms and biofilm formation by Porphyromonas gingivalis, a major pathogen of periodontal disease. Methods and Results Biofilm cell survival was measured using adenosine triphosphate (ATP) bioluminescence. In the presence of EGCg, the ATP level in cells of established biofilms was significantly decreased compared to the controls (P