Short Term Prognosis of Renal Artery Stenosis Secondary to Acute Type B Aortic Dissection With TEVAR.

Short Term Prognosis of Renal Artery Stenosis Secondary to Acute Type B Aortic Dissection With TEVAR.
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TEVAR 治疗继发于急性 B 型主动脉夹层的肾动脉狭窄的短期预后

DOI:
10.3389/fcvm.2021.658952
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发表时间:
2021
影响因子:
3.6
通讯作者:
Zhang H
Zhang H
中科院分区:
医学3区
文献类型:
--
作者:
Li L;Wang M;Li J;Guan X;Xin P;Wang X;Liu Y;Li H;Jiang W;Gong M;Zhang H

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目的:探讨急性 B 型主动脉夹层(ATBAD)胸主动脉腔内修复术(TEVAR)导致的肾动脉狭窄(RAS)对 ATBAD 患者早期预后的影响。方法:我们的研究纳入了国家急性主动脉综合征数据库(AASCN)中 2019 年至 2020 年间接受 TEVAR 的 129 例 ATBAD 患者。患者被分为两组:RAS 组和非 RAS 组。结果:我们的队列中有 21 名 RAS 患者(16.3%)和 108 名非 RAS 患者(83.7%)。在 1 个月的随访期间,我们队列中没有患者死亡。两组术前肌酐清除率(CCr)无显着差异(RAS组为90.6±46.1μmol/L,非RAS组为78.7±39.2μmol/L,P=0.303),但RAS组的估计肾小球滤过率(eGFR)显着低于非RAS组(83.3±25.0 vs.分别为 101.9 ± 26.9 ml/min;P = 0.028)。TEVAR 一个月后,CCr 显着升高(99.0 ± 68.1 vs. 78.5 ± 25.8 ml/min,P = 0.043)和 eGFR(81.7 ± 23.8 vs. 96.0 ± 20.0 ml/min,P = 0.017) RAS 组显着低于非 RAS 组。结论:在ATBAD中,RAS可能在TEVAR术后早期导致急性肾损伤(AKI)。 RAS组高血压发生率较高。这些结果表明 RAS 患者可能需要进一步治疗。
Objective: To determine the effect of renal artery stenosis (RAS) resulting from acute type B aortic dissection (ATBAD) with thoracic endovascular aortic repair (TEVAR) on early prognosis in patients with ATBAD. Methods: A total of 129 ATBAD patients in the National Acute Aortic Syndrome Database (AASCN) who underwent TEVAR between 2019 and 2020 were enrolled in our study. Patients were divided into two groups: the RAS group and the non-RAS group. Results: There were 21 RAS patients (16.3%) and 108 non-RAS patients (83.7%) in our cohort. No patient in our cohort died during the 1-month follow-up. There was no significant difference in preoperative creatinine clearance rate (CCr) between the two groups (90.6 ± 46.1 μmol/L in the RAS group vs. 78.7 ± 39.2 μmol/L in the non-RAS group, P = 0.303) but the RAS group had a significantly lower estimated glomerular filtration rate (eGFR) than the non-RAS group (83.3 ± 25.0 vs. 101.9 ± 26.9 ml/min, respectively; P = 0.028).One month after TEVAR, CCr was significantly higher (99.0 ± 68.1 vs. 78.5 ± 25.8 ml/min, P = 0.043) and eGFR (81.7 ± 23.8 vs. 96.0 ± 20.0 ml/min, P = 0.017) was significantly lower in the RAS group than in the non-RAS group. Conclusions: In ATBAD, RAS could result in acute kidney injury (AKI) in the early stage after TEVAR. The RAS group had a high incidence of hypertension. These results suggest that patients with RAS may need further treatment.
DOI: 10.2215/cjn.11611113
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