Comparison between carotid-femoral and brachial-ankle pulse wave velocity as measures of arterial stiffness
Comparison between carotid-femoral and brachial-ankle pulse wave velocity as measures of arterial stiffness
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DOI：
10.1097/hjh.0b013e32832e94e7
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发表时间：
2009-10-01
影响因子：
4.9
通讯作者：
Ozawa, Toshio
中科院分区：
文献类型：
--
作者：
Tanaka, Hirofumi;Munakata, Masanori;Ozawa, Toshio
背景动脉僵硬是心血管疾病的重要危险因素。颈动脉-股动脉脉搏波速度(CfPWV)是目前公认和公认的反映动脉僵硬程度的指标。一种主要用于亚洲国家的新出现的PWV自动测量方法是臂踝PWV(BaPWV)。方法为了系统地比较这两种方法，我们进行了一项涉及2287名患者的多中心研究。结果baPWV与cfPWV呈显著正相关(r=0.73)。平均baPWV比cfPWV高约20%。CfPWV和baPWV均与年龄(r=0.56和0.64)、收缩压(r=0.49和0.61)和Framingham危险评分(r=0.48和0.63)呈显著正相关。CfPWV和baPWV预测卒中和冠状动脉病变的受试者工作曲线(ROC)下面积相似。结论这些结果表明，cfPWV和baPWV是反映动脉僵硬程度的指标，它们与心血管疾病危险因素和临床事件的关联程度相似。J Hyperten 27：2022-2027(C)2009年沃尔特斯·克鲁沃健康垂直酒吧Lippincott Williams&Wilkins。
Background Arterial stiffness is an important risk factor for cardiovascular disease. Carotid-femoral pulse wave velocity (cfPWV) is the most recognized and established index of arterial stiffness. An emerging automatic measure of PWV primarily used in the Asian countries is brachial-ankle PWV (baPWV). Method To systematically compare these two methodologies, we conducted a multicenter study involving a total of 2287 patients. Results There was a significant positive relation between baPWV and cfPWV (r=0.73). Average baPWV was approximately 20% higher than cfPWV. Both cfPWV and baPWV were significantly and positively associated with age (r=0.56 and 0.64), systolic blood pressure (r=0.49 and 0.61), and the Framingham risk score (r=0.48 and 0.63). The areas under the receiver operating curves (ROCs) of PWV to predict the presence of both stroke and coronary artery disease were comparable between cfPWV and baPWV. Conclusion Collectively, these results indicate that cfPWV and baPWVare indices of arterial stiffness that exhibit similar extent of associations with cardiovascular disease risk factors and clinical events. J Hypertens 27: 2022-2027 (C) 2009 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.