The Future of Vascular Biology and Medicine.
The Future of Vascular Biology and Medicine.
复制标题
DOI：
10.1161/circulationaha.116.023513
复制
发表时间：
2016-06-21
期刊：
影响因子：
37.8
通讯作者：
Leopold JA
中科院分区：
文献类型：
--
作者：
Kinlay S;Michel T;Leopold JA
2604 Circulation 2016年6月21日床是表型不同的，并可能通过与结构细胞的串扰而呈现器官特异性。此外，我们将开始探索机制，通过检查影响血管系统的关键基因-环境的相互作用，如人类和肠道微生物之间的管理个体间的患者变异性。血管研究中的后一个新生领域被进一步讨论，作为血管生物学新前沿的一个例子，可能会在未来的研究中使用上述原则来定义微生物组如何调节心肺血管疾病。
2604 Circulation June 21, 2016 beds are phenotypically different and are likely to take on organ-specific properties through cross-talk with structural cells. In addition, we will begin to explore mechanisms that govern interindividual patient variability by examining key gene-environment interactions that affect the vasculature such as that between humans and commensal microbes. This latter nascent area in blood vessel research is discussed further as an example of a new frontier in vascular biology that will likely use the aforementioned principles in future studies to define how the microbiome regulates cardiopulmonary vascular disease.