Mother-infant interaction in women with depression in pregnancy and in women with a history of depression: the Psychiatry Research and Motherhood - Depression (PRAM-D) study.
Mother-infant interaction in women with depression in pregnancy and in women with a history of depression: the Psychiatry Research and Motherhood - Depression (PRAM-D) study.
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DOI：
10.1192/bjo.2021.52
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发表时间：
2021-05-25
期刊：
影响因子：
5.4
通讯作者：
Pariante CM
中科院分区：
文献类型：
--
作者：
Bind RH;Biaggi A;Bairead A;Du Preez A;Hazelgrove K;Waites F;Conroy S;Dazzan P;Osborne S;Pawlby S;Sethna V;Pariante CM
人们对出生前抑郁对母婴互动质量的影响知之甚少。了解抑郁症，无论是在怀孕期间还是在怀孕前的一生中，是否会破坏产后母婴互动。我们招募了131名怀孕25周的孕妇（51名健康，52名患有妊娠期重度抑郁症，28名有重度抑郁症病史但妊娠健康）。重度抑郁症通过DSM-IV障碍的结构化临床访谈得到证实。用新生儿行为评估量表在6天评估新生儿行为，在8周和12个月时用Crittenden CARE-Index评估母婴互动。在8周和12个月时，抑郁组和只有病史组的两组婴儿与健康的两组婴儿相比，互动质量有所下降。具体来说，在8周时，62%的抑郁组和56%的无病史组得分为最低类别的双同步（表明需要治疗干预），而健康组为37% (P = 0.041)；12个月时，分别有48%和32%的患者得分相同，而健康组为14% （P = 0.003）。在第6天，抑郁组和只有病史组的新生儿表现出减少的社会互动行为，这与母亲的社会经济困难一起，也预示着互动质量，而产后抑郁则不是。无论产后抑郁与否，产前抑郁和终生抑郁史都与母婴互动质量下降有关。临床医生应该意识到这一点，因为怀孕提供了一个识别和干预的机会，以支持发展的关系。
Little is known about the effects of depression before birth on the quality of the mother–infant interaction. To understand whether depression, either in pregnancy or in lifetime before pregnancy, disrupts postnatal mother–infant interactions. We recruited 131 pregnant women (51 healthy, 52 with major depressive disorder (MDD) in pregnancy, 28 with a history of MDD but healthy pregnancy), at 25 weeks’ gestation. MDD was confirmed with the Structured Clinical Interview for DSM-IV Disorders. Neonatal behaviour was assessed at 6 days with the Neonatal Behavioural Assessment Scale, and mother–infant interaction was assessed at 8 weeks and 12 months with the Crittenden CARE-Index. At 8 weeks and 12 months, dyads in the depression and history-only groups displayed a reduced quality of interaction compared with healthy dyads. Specifically, at 8 weeks, 62% in the depression group and 56% in the history-only group scored in the lowest category of dyadic synchrony (suggesting therapeutic interventions are needed), compared with 37% in the healthy group (P = 0.041); 48% and 32%, respectively, scored the same at 12 months, compared with 14% in the healthy group (P = 0.003). At 6 days, neonates in the depression and history-only groups exhibited decreased social-interactive behaviour, which, together with maternal socioeconomic difficulties, was also predictive of interaction quality, whereas postnatal depression was not. Both antenatal depression and a lifetime history of depression are associated with a decreased quality of mother–infant interaction, irrespective of postnatal depression. Clinicians should be aware of this, as pregnancy provides an opportunity for identification and intervention to support the developing relationship.
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扩大健康艺术计划：世界上最大的研究，将基于艺术的心理健康干预措施纳入国家卫生服务。
影响因子：
2.6
作者：
Estevao C;Fancourt D;Dazzan P;Chaudhuri KR;Sevdalis N;Woods A;Crane N;Bind R;Sawyer K;Rebecchini L;Hazelgrove K;Manoharan M;Burton A;Dye H;Osborn T;Jarrett L;Ward N;Jones F;Podlewska A;Premoli I;Derbyshire-Fox F;Hartley A;Soukup T;Davis R;Bakolis I;Healey A;Pariante CM
通讯作者：
Pariante CM
影响因子：
2.1
作者：
Field, Tiffany
通讯作者：
Field, Tiffany
影响因子：
4.5
作者：
Dubber, S.;Reck, C.;Gawlik, S.
通讯作者：
Gawlik, S.
影响因子：
2.2
作者：
Flykt, Marjo;Kanninen, Katri;Punamaki, Raija-Leena
通讯作者：
Punamaki, Raija-Leena
影响因子：
3.3
作者：
CRITTENDEN, PM;BONVILLIAN, JD
通讯作者：
BONVILLIAN, JD