GENETIC EXCHANGE IN SALMONELLA
GENETIC EXCHANGE IN SALMONELLA
复制标题
沙门氏菌的基因交换
DOI：
10.1128/jb.64.5.679-699.1952
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发表时间：
1952
影响因子：
3.2
通讯作者：
J. Lederberg
中科院分区：
文献类型：
--
作者：
N. Zinder;J. Lederberg
对许多不同细菌的遗传研究揭示了它们与高等形式生物的相似之处和一些对比。选择性富集技术在大肠杆菌基因重组研究中的成功应用（Tatum and Lederberg, 1947; Lederberg et al., 1951）表明，类似的方法应该应用于其他细菌。本文介绍了鼠伤寒沙门氏菌和其他血清型沙门氏菌的实验结果。在这些实验中发现的基因交换机制在许多方面不同于大肠杆菌的性重组，因此需要一个新的描述术语，转导。
Genetic investigations with many different bacteria have revealed parallelisms and some contrasts with the biology of higher forms. The successful application of selective enrichment techniques to the study of gene recombination in Escherichia coli (Tatum and Lederberg, 1947; Lederberg et al., 1951) suggestred that a similar approach should be applied to other bacteria. This paper presents the results of such experiments with Salmonella typhimurium a.nd other Salmonella serot,ypes. The mechanism of genetic exchange found in these experiments differs from sexual recombination in E. coli in many respect’s so as t,o warrant a new descriptive term, transduction.