Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype
Psychosocial functioning in a prepubertal and early adolescent bipolar disorder phenotype
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DOI：
10.1097/00004583-200012000-00018
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发表时间：
2000-12-01
影响因子：
13.3
通讯作者：
Gundersen, K
中科院分区：
文献类型：
--
作者：
Geller, B;Bolhofner, K;Gundersen, K
目的：比较青春期前和青春期早期双相情感障碍表型（PEA-BP）样本与两个对照组（即，注意力缺陷多动障碍（ADHD）和社区对照（CC）。方法：有93例PEA-SR（伴或不伴共病ADHD）、81例ADHD和94例CC受试者参与了正在进行的研究，即现象学课程或儿科双相情感障碍。PEA-BP和ADHD组的病例是通过连续新病例确定获得的门诊患者，CC受试者来自三角研究所进行的调查。为了符合研究表型，PEA-BP受试者需要目前患有DSM-IV躁狂或轻躁狂，并将夸大和/或夸大作为一个标准。PF的评估是由经验丰富的研究护士谁是盲目的组状态。母亲和儿童分别采访了学龄儿童心理社会时间表修订。结果如下：与ADHD和CC被试相比，PEA-BP被试在评估母子温暖、母子和父子紧张以及同伴关系的项目上有更大的损害。结论：临床医生在计划干预时需要考虑PF缺陷。在PEA-BP组中，性欲亢进的发生率为43%，
Objective: To compare psychosocial functioning (PF) in a prepubertal and early adolescent bipolar disorder phenotype (PEA-BP) sample to two comparison groups, i.e., attention-deficit/hyperactivity disorder (ADHD) and community controls (CC). Method: There were 93 PEA-SR (with or without comorbid ADHD), 81 ADHD, and 94 CC subjects who were participants in an ongoing study, me Phenomenology ano Course or Pediatric Bipolar Disorders. Cases in the PEA-BP and ADHD groups were outpatients obtained by consecutive new case ascertainment, and CC subjects were from a survey conducted by the Research Triangle Institute. To fit the study phenotype, PEA-BP subjects needed to have current DSM-IV mania or hypomania with elation and/or grandiosity as one criterion. Assessments for PF were by experienced research nurses who were blind to group status. Mothers and children were separately interviewed with the Psychosocial Schedule for School Age Children-Revised. Results: Compared with both ADHD and CC subjects, PEA-BP cases had significantly greater impairment on items that assessed maternal-child warmth, maternal-child and paternal-child tension, and peer relationships. Conclusions: Clinicians need to consider PF deficits when planning interventions. In the PEA-BP group, there was a 43% rate of hypersexuality with a