AN ANALYSIS OF O2 DEBT CONTRACTED IN SUBMAXIMAL EXERCISE

AN ANALYSIS OF O2 DEBT CONTRACTED IN SUBMAXIMAL EXERCISE
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DOI:
10.1152/jappl.1970.29.5.547
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发表时间:
1970-01-01
影响因子:
3.3
通讯作者:
MARGARIA, R
MARGARIA, R
中科院分区:
医学2区
文献类型:
--
作者:
DIPRAMPE.PE;DAVIES, CTM;MARGARIA, R

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DI PRAMPERO,P. IL,CTM DAVIES,P. CERETELLI,AND R.玛格丽特。02年次极量行使债务契约分析。J. AppZ. Physiol.29(5):547-551. 1970.-进行次极量运动的人的O2摄入动力学# OS)在从轻度工作到较重工作的过渡中似乎比从休息到工作的过渡(t1/z= 30 s)更快(tr,z= 17 s)。在开始行使时Vo的差异,即02债务总额,相应地减少。这种减少大概不会以净O2负债为代价发生;这是在稳态下存在于肌肉中的分裂磷酸原的量的表达,应该仅与工作强度相关,与肌肉活动的先前历史无关。这大概是由于a)当运动从休息开始时身体的O2储存的更大利用和B)由糖原形成一定量的LA。研究发现,在工作开始时,这种情况会在一定程度上发生,但在从轻度运动到重度运动的过渡过程中则不会发生。在从轻度到较重的工作的过渡中,只有总的无乳02债务受到影响,在这种情况下,02摄取的速度将趋向于接近净无乳02债务的收缩速度。02债务,总债务和净债务在人类中已经发现,在不涉及乳酸产生的次极量运动中,在从休息到工作的过渡期间以及在立即恢复期间的O2消耗作为时间的指数函数而变化,这些过程的J 1/A具有相同的数量级~ 30秒(s)(1,2,7,8,12,13)。类似地,在离体的狗腓肠肌中,运动开始时的O2摄取已显示为指数函数,然而其具有仅约16 s的tl/2(14);恢复期中O2摄取过程的降低也比人中更快(tl,z= 20 s)。复苏的缓慢下降意味着相应的更大的02债务。在人和分离的肌肉中发现的O2负债之间的差异归因于这样的事实,即在人中从呼吸气体交换测量的O2负债是总O2负债,即,它包括从身体的O2储存中抽取的一定量的O2(12)。因此,在总O2负债和净O2负债之间进行了区分;后者仅指示从氧化以外的来源提取的能量,并且在次最大工作中,基本上由肌肉中的分裂磷酸原(ATP+ CP)的量给出
DI PRAMPERO, P. IL, CTM DAVIES, P. CERRETELLI, AND R. MARGARIA. An analysis of 02 debt contracted in submaximal exercise. J. AppZ. Physiol. 29 (5): 547-551. 1970.-The kinetics of 02 uptake# OS) in man performing a submaximal exercise, in the transition from light to heavier work appears to be faster (tr, z= 17 s) than in the transition from rest to work (tl/z= 30 s). The difference in Vo, at the onset of exercise, ie, the gross 02 debt, is reduced correspondingly. This reduction presumably does not take place at the expense of the net 02 debt; this, being the expression of the amount of split phosphagen present in the muscle at steady state, should be related only to the work intensity, independent of the previous history of muscle activity. It is presumably due a) to the greater utilization of the 02 stores of the body when the exercise starts from rest and b) to a certain amount of LA formation from glycogen. This has been found to take place to a limited extent at the onset of work, but not in the transition from light to heavier exercise. In the transition from mild to heavier work only the gross alactic 02 debt is then affected, The velocity of the 02 uptake in this condition would tend to approach the velocity of the contraction of the net alactic 02 debt.02 debt, gross and netIT HAS BEEN FOUND in man that, in submaximal exercise not involving lactic acid production, the 02 consumption during the transition from rest to work and during the immediate recovery period changes as an exponential function of time, the j 1/a of the processes being of the same order of magnitude~ 30 second (s)(1, 2, 7, 8, 12, 13). Similarly in the isolated dog gastrocnemius the O2 uptake at the onset of exercise has been shown to be an exponential function, which however has a tl/2 of only about 16 s (14); the decrease of the 02 uptake process in the recovery phase is also faster than in man (tl, z= 20 s). A slow fall in recovery ii02 implies a correspondingly larger 02 debt. The difference between the O2 debt found in man and in the isolated muscle has been attributed to the fact that the 02 debt, as measured in man from the respiratory gas exchange is the gross 02 debt, ie, it includes a certain amount of 02 drawn from the O2 stores of the body (12). A distinction has therefore been made between gross and net 02 debt; this last only is indicative of the energy drawn from sources other than oxidations and is given substantially, in submaximal work, by the amount of split phosphagen(ATP+ CP) in the muscles