QNet:: An agglomerative method for the construction of phylogenetic networks from weighted quartets

QNet:: An agglomerative method for the construction of phylogenetic networks from weighted quartets
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DOI:
10.1093/molbev/msl180
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发表时间:
2007-02-01
影响因子:
10.7
通讯作者:
Moulton, Vincent
Moulton, Vincent
中科院分区:
生物学1区
文献类型:
--
作者:
Grunewald, Stefan;Forslund, Kristoffer;Moulton, Vincent

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我们提出了QNet,一种从加权四元组树构建分裂网络的方法。QNet可以被视为基于距离的邻居网络(NNet)方法的四元组模拟。就像NNet一样,QNet的工作原理是聚集计算分类群集合的循环加权分割,然后用平面分割网络表示。为了说明QNet的适用性,我们将其应用于以前发表的沙门氏菌数据集。我们的结论是,QNet可以提供一个有用的替代NNet,如果距离数据不可用或基于字符的方法是首选。此外,它还可以用来帮助确定基于四元组的树构建方法何时可能适合或不适合给定的数据集。QNet可免费下载。
We present QNet, a method for constructing split networks from weighted quartet trees. QNet can be viewed as a quartet analogue of the distance-based Neighbor-Net (NNet) method for network construction. Just as NNet, QNet works by agglomeratively computing a collection of circular weighted splits of the taxa set which is subsequently represented by a planar split network. To illustrate the applicability of QNet, we apply it to a previously published Salmonella data set. We conclude that QNet can provide a useful alternative to NNet if distance data are not available or a character-based approach is preferred. Moreover, it can be used as an aid for determining when a quartet-based tree-building method may or may not be appropriate for a given data set. QNet is freely available for download.