Binding and internalization of microorganisms by integrin receptors

Binding and internalization of microorganisms by integrin receptors
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DOI:
10.1016/0966-842x(94)90338-7
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发表时间:
1994-01-01
影响因子:
15.9
通讯作者:
Van Nhieu, Guy Tran
Van Nhieu, Guy Tran
中科院分区:
生物学1区
文献类型:
--
作者:
Isberg, Ralph R.;Van Nhieu, Guy Tran

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许多微生物病原体结合宿主细胞整合素受体。这些相互作用要么由结合微生物的宿主蛋白促进,要么由病原体编码的表面定位配体促进。附着有助于微生物的细胞外黏附或宿主细胞的内化。
Many microbial pathogens bind host-cell integrin receptors. These interactions are promoted either by a host protein binding the microorganism or by a surface-localized ligand encoded by the pathogen. Attachment facilitates extracellular adhesion of the microorganism or internalization by the host cell.