Generic Ledipasvir-Sofosbuvir Treatment for Adolescents With Chronic Hepatitis C Virus Infection

Generic Ledipasvir-Sofosbuvir Treatment for Adolescents With Chronic Hepatitis C Virus Infection
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DOI:
10.1093/jpids/piz041
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发表时间:
2020-07-01
影响因子:
3.2
通讯作者:
Aziz, Hossam Abdel
Aziz, Hossam Abdel
中科院分区:
医学3区
文献类型:
--
作者:
Fouad, Hanan M.;Sabry, Magda A.;Aziz, Hossam Abdel

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我们评估了ledipasvir-sofosbuvir治疗埃及青少年丙型肝炎病毒感染的安全性和有效性,并将结果与品牌形式的治疗结果进行了比较。通用形式导致高响应率,肝功能显著改善和轻度不良反应。这些结果与品牌形式的价格降低的结果相当。
We assessed the safety and efficacy of a generic form of ledipasvir-sofosbuvir for the treatment of hepatitis C virus infection in Egyptian adolescents and compared the results with those of treatment with the brand-named form. The generic form resulted in a high response rate, significant improvement in liver function, and mild adverse effects. These results are comparable with those of the brand form at a reduced price.