Refractory pyoderma gangrenosum treated with infliximab in an infant
Refractory pyoderma gangrenosum treated with infliximab in an infant
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英夫利昔单抗治疗婴儿难治性坏疽性脓皮病
DOI：
10.1111/ced.12297
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发表时间：
2014
影响因子：
4.1
通讯作者：
E. López‐Bran
中科院分区：
文献类型：
--
作者：
L. Campos;A. Conde;E. Aleo;E. Toledano;E. López‐Bran
我们报告一例11个月大的男婴，患有严重顽固性坏疽脓皮病，对泼尼松、氨苯松和环孢素无效。英夫利昔单抗治疗耐受性良好，临床反应良好，已持续15个月。对儿童这种疾病的特点和英夫利昔单抗在婴儿中的应用进行了综述。
We report the case of an 11‐month‐old boy with severe recalcitrant pyoderma gangrenosum refractory to prednisone, dapsone and ciclosporin. Treatment with infliximab was well tolerated, and resulted in an excellent clinical response that has been sustained for 15 months. The characteristics of this condition in children and the use of infliximab in infants are both reviewed.