Infective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments.

Infective Endocarditis in Persons Who Use Drugs: Epidemiology, Current Management, and Emerging Treatments.
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DOI:
10.1016/j.idc.2020.06.004
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发表时间:
2020-09
影响因子:
4.4
通讯作者:
Barocas JA
Barocas JA
中科院分区:
医学3区
文献类型:
--
作者:
Schranz A;Barocas JA

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严重的细菌和真菌感染,如感染性心内膜炎(IE)是注射毒品(PWID)的人最常见的医疗并发症。1-3 IE曾经主要影响老年人和免疫功能低下的人,但在年轻人中越来越常见,作为注射药物使用的并发症。1,4 - 8这些感染可导致心脏手术、9败血症和死亡。10,11在此,我们回顾了流行病学,当前和新兴的管理策略,临床考虑和争议,并提出了一种管理注射药物使用相关感染性心内膜炎(IDU-IE)的方法。
Serious bacterial and fungal infections such as infective endocarditis (IE) are among the most common medical complications in persons who inject drugs (PWID). 1–3 IE once primarily impacted older adults and immunocompromised persons, but is increasingly common among younger persons as complications of injection drug use. 1, 4–8 These infections can result in cardiac surgery, 9 sepsis, and death. 10, 11 Herein, we review the epidemiology, current and emerging management strategies, clinical considerations and controversies, and propose an approach for the management of injection drug use-related infective endocarditis (IDU-IE).
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