Out of Date or Best Before? A Commentary on the Relevance of Economic Evaluations Over Time
Out of Date or Best Before? A Commentary on the Relevance of Economic Evaluations Over Time
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DOI：
10.1007/s40273-021-01116-4
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发表时间：
2021-12-06
影响因子：
4.4
通讯作者：
Elvidge, Jamie
中科院分区：
文献类型：
--
作者：
Shields, Gemma E.;Pennington, Becky;Elvidge, Jamie
时间对历史经济评估的适用性和相关性的影响可能是相当大的。忽视这一点可能会导致使用薄弱或无效的证据来为重要的研究问题或资源分配决策提供信息，因为与最近进行的类似研究相比，历史经济评估可能得出不同的结论。导致证据过时的因素有很多，包括相关决策问题的变化(例如，比较器)、参数的变化(例如成本、效用和资源使用)和方法更新(例如，关于不确定性分析的建议)。审查经济评估的研究人员需要考虑，如果评估重复到不再有帮助或提供信息的程度，随着时间的推移，变化是否会影响研究设计和结果。在本文中，我们总结了这些关键问题，并就研究人员如何以及是否可以未来证明他们的经济评估提出建议。
The impact of time on the applicability and relevance of historical economic evaluations can be considerable. Ignoring this may lead to the use of weak or invalid evidence to inform important research questions or resource allocation decisions, as historical economic evaluations may have reached different conclusions compared to if a similar study had been conducted more recently. There are multiple factors that contribute towards evidence becoming outdated including changes to the relevant decision problem (e.g. comparators), changes to parameters (such as costs, utilities and resource use) and methodological updates (e.g. recommendations on uncertainty analysis). Researchers reviewing economic evaluations need to consider whether changes over time would influence the study design and results if the evaluation were repeated, to the extent that it is no longer helpful or informative. In this paper, we summarise these key issues and make recommendations about how and whether researchers can future proof their economic evaluations.