A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men.

A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men.
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DOI:
10.1097/qai.0b013e31818d5def
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发表时间:
2008-12-15
期刊:
Journal of acquired immune deficiency syndromes (1999)
影响因子:
--
通讯作者:
Healthy Living Project Team
Healthy Living Project Team
中科院分区:
其他
文献类型:
--
作者:
Morin SF;Shade SB;Steward WT;Carrico AW;Remien RH;Rotheram-Borus MJ;Kelly JA;Charlebois ED;Johnson MO;Chesney MA;Healthy Living Project Team

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研究解释认知行为干预对降低艾滋病毒感染的男男性行为者(MSM)中艾滋病毒传播风险的影响的因素。在筛选的1,910名感染艾滋病毒的男男性行为者中,616名被认为有传播艾滋病毒风险的参与者被随机分为15个阶段,分别进行认知行为干预(n = 301)或等候名单对照(n = 315)。与先前的意向治疗结果一致,干预组和对照组的男男性行为中传播风险行为总体上都有所减少,在5、10、15和20个月的评估中观察到显著的干预效果(风险比= 0.78,风险比= 0.78)。62年,。48、和。分别为38)。这些与干预有关的艾滋病毒传播风险行为的减少似乎部分是由于持续的血清分类做法。在5个月和10个月的评估中,干预条件下的男男性行为者报告的性伴侣感染艾滋病毒的比例明显更高(风险比= 1.14和1.18)。健康生活项目是一项认知行为干预,在减少男男性接触者之间的传播风险行为方面是有效的。这似乎在很大程度上是由于干预条件下的男同性恋者报告了持续的血清分选实践。
To examine factors that explain the effect of a cognitive-behavioral intervention on reductions in HIV transmission risk among HIV-infected men who have sex with men (MSM). Of the 1,910 HIV-infected MSM screened, 616 participants considered to be at risk of transmitting HIV were randomized to a 15-session, individually delivered cognitive-behavioral intervention (n = 301) or a wait-list control (n = 315). Consistent with previous intent-to-treat findings, there was an overall reduction in transmission risk acts among MSM in both intervention and control arms, with significant intervention effects observed at the 5, 10, 15, and 20 month assessments (Risk Ratios = .78, .62, .48, and .38, respectively). These intervention-related decreases in HIV transmission risk acts appeared to be partially due to sustained serosorting practices. MSM in the intervention condition reported a significantly greater proportion of sexual partners who were HIV-infected at the 5 and 10 month assessments (Risk Ratio = 1.14 and 1.18). The Healthy Living Project, a cognitive-behavioral intervention, is efficacious in reducing transmission risk acts among MSM. This appears to have been due in large part to the fact that MSM in the intervention condition reported sustained serosorting practices.