The role of cognitive rehabilitation in people with type 2 diabetes: A study protocol for a randomized controlled trial.
The role of cognitive rehabilitation in people with type 2 diabetes: A study protocol for a randomized controlled trial.
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DOI：
10.1371/journal.pone.0285553
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发表时间：
2023
期刊：
影响因子：
3.7
通讯作者：
Kim, Jeeyeon
中科院分区：
文献类型：
--
作者：
Cuevas, Heather;Stuifbergen, Alexa K.;Hilsabeck, Robin C.;Sales, Adam;Wood, Shenell;Kim, Jeeyeon
今天，认知功能障碍的患病率和糖尿病的患病率正在增加。研究表明，糖尿病会增加认知障碍的风险，认知障碍使糖尿病的自我管理更具挑战性。糖尿病自我管理对于良好的血糖控制至关重要，它要求患者吸收有关其复杂疾病的知识，并参与诸如血糖自我监测和药物管理等活动。测试全面的认知康复干预--糖尿病患者的记忆、注意力和解决问题的技能(MAPSS-DM)计划。我们的中心假设是，参与MAPSS-DM干预的参与者将改善记忆和执行功能，增加对补偿性认知技能的使用，并改善自我管理。我们还将探讨葡萄糖变异性在这些变化中的作用。这是一项随机对照试验。66名有认知障碍和2型糖尿病的参与者将被分配到完全MAPSS-DM干预组或积极对照组。参与者将在干预前后使用连续的血糖监测来确定血糖变异性的变化。所有参与者还将在三个时间点通过问卷调查和神经心理学测试进行系统评估：基线、干预后立即和干预后3个月。这项研究将通过解决糖尿病管理中的认知功能来填补一个重要的空白。糖尿病与认知老化加速有关，认知缺陷与较差的自我管理有关，认知康复导致的认知表现的改善可以转化为日常生活中表现的改善，并可能转化为糖尿病的自我管理。因此，这项拟议研究的结果可能会为支持认知功能和糖尿病自我管理的策略提供参考，并通过使用连续血糖监测提供对认知功能的新的机械性见解。试验注册：这项研究已在ClinicalTrials.gov(NCT04831775)上注册。
Today, the prevalence of cognitive dysfunction and the prevalence of diabetes are increasing. Research shows that diabetes increases cognitive impairment risk, and cognitive impairment makes diabetes self-management more challenging. Diabetes self-management, essential to good glycemic control, requires patients to assimilate knowledge about their complex disease and to engage in activities such as glucose self-monitoring and the management of their medications. To test a comprehensive cognitive rehabilitation intervention—the Memory, Attention, and Problem-Solving Skills for Persons with Diabetes (MAPSS-DM) program. Our central hypothesis is that participants who take part in the MAPSS-DM intervention will have improved memory and executive function, increased use of compensatory cognitive skills, and improved self-management. We will also explore the role of glucose variability in those changes. This is a randomized controlled trial. Sixty-six participants with cognitive concerns and type 2 diabetes will be assigned to either the full MAPSS-DM intervention or an active control. Participants will use continuous glucose monitoring pre- and post-intervention to identify changes in glycemic variability. All participants will also be evaluated systematically via questionnaires and neuropsychological tests at three timepoints: baseline, immediately post-intervention, and 3 months post-intervention. This study will fill an important gap by addressing cognitive function in the management of diabetes. Diabetes is related to accelerated cognitive aging, cognitive deficits are related to poorer self-management, and improvements in cognitive performance as a result of cognitive rehabilitation can translate into improved performance in everyday life and, potentially, diabetes self-management. The results of the proposed study will therefore potentially inform strategies to support cognitive function and diabetes self-management, as well as offer new mechanistic insights into cognitive function through the use of continuous glucose monitoring. Trial registration: This study has been registered at ClinicalTrials.gov (NCT04831775).
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影响因子：
1.6
作者：
Cuevas, Heather E.;Stuifbergen, Alexa K.;Ward, Catherine
通讯作者：
Ward, Catherine
通过连续葡萄糖监测与2型糖尿病患者中亚临床糖尿病多神经病的连续葡萄糖监测评估的血糖变异性的关联。
影响因子：
3.2
作者：
Pan J;Yan X;Li F;Zhang Y;Jiang L;Wang C
通讯作者：
Wang C
影响因子：
3.8
作者：
Brasser, Maria;Fruhholz, Sascha;Schneeberger, Andres R.;Ruschetti, Gian G.;Schaerli, Rahel;Haner, Michele;Studer-Luethi, Barbara
通讯作者：
Studer-Luethi, Barbara
影响因子：
8.2
作者：
Rutter, Martin K.
通讯作者：
Rutter, Martin K.
影响因子：
5
作者：
Pratley RE;Rosenstock J;Heller SR;Sinclair A;Heine RJ;Kiljański J;Brusko CS;Duan R;Festa A
通讯作者：
Festa A