Herpes simplex virus encephalitis during treatment with etanercept
Herpes simplex virus encephalitis during treatment with etanercept
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DOI：
10.3109/00365548.2013.849816
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发表时间：
2014-02-01
影响因子：
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通讯作者：
Parenti, David M.
中科院分区：
文献类型：
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作者：
Crusio, Robbert H. J.;Singson, Stephanie V.;Parenti, David M.
肿瘤坏死因子α（TNF-α）抑制剂广泛用于治疗各种炎性病症。它们与感染风险增加有关。我们报告一例单纯疱疹病毒1型（HSV-1）脑炎的患者接受依那西普和审查文献的TNF-α和TNF-α抑制剂，及其在单纯疱疹病毒脑炎的病理生理学的重要性。
Tumor necrosis factor alpha (TNF-alpha) inhibitors are widely used for the treatment of various inflammatory conditions. They are associated with an increased risk for infections. We report a case of herpes simplex virus type 1 (HSV-1) encephalitis in a patient receiving etanercept and review the literature on TNF-alpha and TNF-alpha inhibitors, and their importance in the pathophysiology of herpes simplex encephalitis.