New ADCY3 Variants Dance in Obesity Etiology.
New ADCY3 Variants Dance in Obesity Etiology.
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新的 ADCY3 变体在肥胖病因学中起舞。
DOI:
10.1016/j.tem.2018.02.004
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发表时间:
2018
期刊:
影响因子:
--
通讯作者:
Fu Xianghui
中科院分区:
文献类型:
--
作者:
Tian Yan;Peng Boqiang;Fu Xianghui
The genetic etiology for obesity-related traits remains elusive. Recent studies link novel ADCY3 variants to obesity and diabetes, and identify an important role of ADCY3-mediated signaling at neuronal primary cilia in the predisposition of obesity. These findings provide new information on obesity etiology and suggest potential anti-obesity therapeutic strategies.